What are Tricyclics?

Tricyclics are antidepressants that inhibit the inactivation of the norepinephine and serotonin in the brain. The drugs are highly effective in relieving the symptoms in depressed patients and can also be used in the treatment of attention deficit hyperactivity disorder.

Tricyclic antidepressants seem to work best for pain caused by low back pain, migraine, tension headache, arthritis, and other painful conditions. These drugs are effective in relieving pain independent of their effects on depression.

TCAs have also been linked to sudden death syndrome in children. For this reason, many clinicians put them at the bottom of the list of ADHD medications for children. TCAs can also be risky for substance abusers. Before starting TCA treatment for children, doctors recommend getting a baseline EKG in addition to monitoring side effects.

Side effects

The side effect associated with Tricyclic antidepressants are usually mild. These may include:

• Dry mouth
• Drowsiness
• Constipation
• Weight gain
• Difficulty with urination
• Blood pressure changes
• Risk of severe mood and behavior changes, including suicidal thoughts (Young adults may be at a higher risk for this side effect.)

To reduce the risk of side effects, your doctor will prescribe a low...

Possible side effects include:

• Dizziness
• Dry mouth
• Blurred vision
• Constipation
• Difficulty urinating
• Weight gain
• Low blood pressure
• Sexual dysfunction
• Rapid heart rate
• Risk of severe mood and behavior changes, including suicidal thoughts in some patients (Young adults may be at a higher risk for this side effect.)