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Adenosine monophosphate (AMP) is a substance the body creates on the way to making adenosine triphosphate (ATP), a source of energy used throughout the body. ATP is so ubiquitous in the body it is sometimes called the body’s “energy currency.”
Based on highly preliminary evidence, AMP has been recommended as a treatment for shingles and photosensitivity .
In adults, infection by the virus herpes zoster can cause a condition known as shingles. The initial shingles attack generally abates in a couple of weeks, but symptoms can go on to become chronic. This condition is called post-herpetic neuralgia (PHN). Some evidence hints that people with herpes zoster infection may have lower than normal levels of AMP. On this slim basis, AMP has been studied as a possible treatment for initial shingles symptoms as well as for preventing PHN.
In a double-blind, placebo-controlled study of 32 people with shingles, AMP was injected three times a week for 4 weeks. 1 At the end of the 4-week treatment period, 88% of those treated with AMP were pain free versus only 43% in the placebo group; all participants still in pain were then given AMP, and no...
Safety Issues
In the human studies performed, use of oral AMP has not been associated with any side effects. However, it has been suggested that use of supplemental AMP could potentially decrease immunity. 2 Safety in young children, pregnant or nursing women, or people with severe liver or kidney disease has not been established.