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Therapeutic Uses
Preliminary evidence, including small, double-blind trials, suggests that tyrosine supplements may help fight fatigue and improve memory and mental function in people who are deprived of sleep or exposed to other forms of stress . 1 Based on the findings, mentioned in the above paragraph, it has been inferred that tyrosine might enhance alertness in people suffering from jet lag , but this has not been studied directly.
Tyrosine may also provide some temporary benefit for attention deficit disorder (ADD) , but the benefits appear to wear off in a couple of weeks. 2 Tyrosine is said to work better for this purpose when it is combined in an "amino acid cocktail" along with gamma-aminobutyric acid (GABA), phenylalanine , and glutamine ; however, there is no scientific evidence to support this use.
Although one extremely tiny study found tyrosine helpful for depression ; 3 a larger study found no evidence of benefit. 4 Tyrosine has also been suggested for enhancing sports performance . However, in a double-blind study of 20 men, one-time use of tyrosine at a dose 150 mg per kilogram body weight failed to improve any measurement of muscular performance. 5
References
- Neri DF, Wiegmann D, Stanny RR, et al. The effects of tyrosine on cognitive performance during extended wakefulness. Avit Space Environ Med. 1995;66:313-319.
- Eisenberg MD, Asnis GM, van Praag HM, et al. Effect of tyrosine on attention deficit disorder with hyperactivity. J Clin Psychiatry. 1988;49:193-195.
- Gibson C, Gelenberg A. Tyrosine for the treatment of depression. Adv Biol Psychiatry. 1983;10:148-159.
- Gelenberg AJ, Wojcik JD, Falk WE, Baldessarini RJ, Zeisel SH, Schoenfeld D, Mok GS. Tyrosine for depression: a double-blind trial. J Affect Disord. 19(2):125-32.
- Sutton EE, Coill MR, Deuster PA. Ingestion of tyrosine: effects on endurance, muscle strength, and anaerobic performance. Int J Sport Nutr Exerc Metab. 15(2):173-85.
