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What Is Tribulus terrestris Used for Today?
Studies performed in Bulgaria are the primary source of most current health claims regarding tribulus. According to this research, tribulus increases levels of various hormones in the steroid family, including testosterone, DHEA, and estrogen, and for this reason improves sports performance , fertility in men and women , sexual function (again in men and women ), and symptoms of menopause (such as hot flashes). 1 2 3 4 Unfortunately, the design of these studies appears to fall far short of modern scientific standards, and there has not been any trustworthy scientific confirmation of these supposed benefits. One well-designed study failed to find that tribulus affects male sex hormone levels in young men. 5 Other studies that are far too preliminary to prove anything at all are quoted as proving that tribulus is helpful for the treatment of angina , high cholesterol , diabetes , and muscle spasms, and for the prevention of kidney stones . 6 7 A properly designed, though small, human study compared the effects of tribulus (3.21 mg per kilogram of body weight—for example, 292 mg daily for a 200-lb man) against placebo on body composition and endurance among 15 men engaged in resistance training. 8 At the end of the 8-week study, the only significant difference between the treatment and placebo groups was that the placebogroup showed greater gains in endurance!
Another double-blind, placebo-controlled study enrolled 22 athletes and followed them for five weeks. 9 The dose used in this trial was fixed at 450 mg daily for all participants. No benefits were seen.
References
- Kumanov F, Bozadzhieva E, Andreeva M, et al. Clinical trial of the drug Tribestan. Savr Med. 1982;4:211-215.
- Protich M, Tsvetkov D, Nalbanski B, et al. Clinical trial of the preparation Tribestan in infertile men. Akush Ginekol. 1983;22:326-329.
- Tanev G, Zarkova S. Toxicological studies on Tribestan. Cited in: Zarkova S. Tribestan: Experimental and Clinical Investigations. Chemical Pharmaceutical Research Institute, Sofia; 1985.
- Viktorov IV, Kaloyanov AL, Lilov L, et al. Clinical investigation on Tribestan in males with disorders in the sexual function. Med-Biol Inf. 1982.
- Neychev VK, Mitev VI. The aphrodisiac herb Tribulus terrestris does not influence the androgen production in young men. J Ethnopharmacol. 2005 Jun 30. [Epub ahead of print]
- Wang B, Ma L, Liu T. 406 cases of angina pectoris in coronary heart disease treated with saponin of Tribulus terrestris [in Chinese; English abstract]. Chung Hsi I Chieh Ho Tsa Chih. 1990;10:85-87.
- Adaikan PG, Gauthaman K, Prasad RN, Ng SC. Proerectile pharmacological effects of Tribulus terrestris extract on the rabbit corpus cavernosum. Ann Acad Med Singapore. 29(1):22-6.
- Antonio J, Uelmen J, Rodriguez R, et al. The effects of Tribulus terrestris on body composition and exercise performance in resistance-trained males [abstract]. Int J Sport Nutr Exerc Metab. 2000;10:208-215.
- Rogerson S, Riches CJ, Jennings C, Weatherby RP, Meir RA, Marshall-Gradisnik SM. The effect of five weeks of Tribulus terrestris supplementation on muscle strength and body composition during preseason training in elite rugby league players. J Strength Cond Res. 21(2):348-53.