Sitaxsentan Side Effects and Warnings

What are the precautions when taking this medicine?

• Check medicines with healthcare provider. This medicine may not mix well with other medicines.

• Avoid or limit alcohol intake (includes wine, beer, and liquor) to less than 3 drinks a day. Drinking too much alcohol may increase the risk of liver disease.

• Birth control pills and other hormone-based birth control may not work to prevent pregnancy. Use another form of birth control while taking this medicine.

What are some possible side effects of this medicine?

• Headache.

• Flushing.

• Swelling.

• Nausea or vomiting. Small frequent meals, frequent mouth care, sucking hard, sugar-free candy, or chewing sugar-free gum may help.

• Nasal congestion.

• Anemia can rarely occur.

• Liver damage can rarely occur.

Reasons to call healthcare provider immediately

• If you suspect an overdose, call your local poison control center or emergency department immediately.

• Signs of a life-threatening reaction. These include wheezing; chest tightness; fever; itching; bad cough; blue skin color; fits; or swelling of face, lips, tongue, or throat.

• Difficulty breathing.

• Severe belly pain.

• Severe nausea or vomiting.

• Not able to eat.

• Dark urine or yellow skin or eyes.

• Feeling extremely tired or weak.

• Significant weight gain.

• For females, if you become pregnant while taking this medicine.

• Any rash.

• No improvement in condition or feeling worse.