Sitagliptin and Metformin Side Effects and Warnings

What are the precautions when taking this medicine?

• Wear disease medical alert identification.

• You should stop this medicine for 2 days after an x-ray with dye.

• Use caution if you are having surgery, if you have a heart attack, severe infection, or stroke, or if you are 80 years of age or older and have not had your kidney function tested.

• If you have gallbladder disease, talk with healthcare provider.

• If you have lung disease, talk with healthcare provider.

• If you have pancreatitis, talk with healthcare provider.

• If you have a weakened heart, talk with healthcare provider.

• Do not drive if blood sugar has been low. There is a greater risk of an accident.

• Check medicines with healthcare provider. This medicine may not mix well with other medicines.

• Avoid alcohol (includes wine, beer, and liquor).

• Tell healthcare provider if you are pregnant or plan on getting pregnant.

• Tell healthcare provider if you are breast-feeding.

What are some possible side effects of this medicine?

• Low blood sugar. Signs include anger, shaking, fast heartbeat, confusion, or sweating. Keep hard candies, glucose tablets, liquid glucose, or juice on hand for low blood sugar.

• Belly pain.

• Nausea or vomiting. Small frequent meals, frequent mouth care, sucking hard, sugar-free candy, or chewing sugar-free gum may help.

• Diarrhea.

• Headache.

• Sore throat.

• Nasal congestion.

• Runny nose.

• Abnormal taste. This is usually reversible.

• Severe allergic reactions can rarely occur.

• Blood acidity (lactic acidosis) may rarely occur.

Reasons to call healthcare provider immediately

• If you suspect an overdose, call your local poison control center or emergency department immediately.

• Signs of a life-threatening reaction. These include wheezing; chest tightness; fever; itching; bad cough; blue skin color; fits; or swelling of face, lips, tongue, or throat.

• Signs or symptoms of infection. These include a fever of 100.5 degrees or higher, chills, severe sore throat, ear or sinus pain, cough, increased sputum or change in color, painful urination, mouth sores, wound that will not heal, or anal itching or pain.

• Very low blood sugar or very high blood sugar.

• Severe dizziness.

• Difficulty breathing.

• Feeling cold.

• Severe belly pain.

• Severe nausea or vomiting.

• Severe diarrhea.

• Severe muscle pain or weakness.

• Not able to eat.

• Feeling extremely tired or weak.

• Any rash.

• No improvement in condition or feeling worse.