Raloxifene Side Effects and Warnings

What are the precautions when taking this medicine?

• If you have any circulation problems, talk with healthcare provider.

• If you have heart disease, talk with healthcare provider.

• If you have high triglycerides, talk with healthcare provider.

• If you have kidney disease, talk with healthcare provider.

• If you have liver disease, talk with healthcare provider.

• Do not take colestipol or cholestyramine within 4 hours of this medicine.

• Check medicines with healthcare provider. This medicine may not mix well with other medicines.

• Limit alcohol intake (includes wine, beer, and liquor).

• Avoid being immobile for long periods of time (long trips, bedrest following surgery). Not moving for long periods may increase your risk of blood clots. Resume normal activity as soon as possible.

What are some possible side effects of this medicine?

• Hot flashes. Wearing layers of clothes or summer clothes and cool environment may help.

• Headache.

• Nausea or vomiting. Small frequent meals, frequent mouth care, sucking hard, sugar-free candy, or chewing sugar-free gum may help.

• Diarrhea.

• Joint pain.

• Leg cramps.

• Inability to sleep.

• For females, vaginal yeast infection. Report itching or discharge.

Reasons to call healthcare provider immediately

• If you suspect an overdose, call your local poison control center or emergency department immediately.

• Signs of a life-threatening reaction. These include wheezing; chest tightness; fever; itching; bad cough; blue skin color; fits; or swelling of face, lips, tongue, or throat.

• Signs or symptoms of depression, suicidal thoughts, nervousness, emotional ups and downs, abnormal thinking, anxiety, or lack of interest in life.

• Chest pain or pressure.

• Difficulty breathing.

• Swelling or pain of leg or arm.

• Severe headache.

• Severe nausea or vomiting.

• Severe diarrhea.

• Significant weight gain.

• Sudden change in vision, eye pain, or irritation.

• Any rash.

• A lump in the breast or breast tenderness.

• For females, menstrual changes. These include lots of bleeding, spotting, or bleeding between cycles.

• No improvement in condition or feeling worse.