Oxycodone and Ibuprofen Overview

(oks i KOE done & eye byoo PROE fen)

Combunox™

Analgesic, Opioid; Nonsteroidal Anti-inflammatory Drug (NSAID), Oral

• This medicine may increase the risk of heart attack, stroke, and high blood pressure. This has been observed with long-term use or at critical times (right after heart surgery). Use caution if you have risk factors for heart disease (high blood pressure, high cholesterol, overweight, diabetes, cigarette smoking, male older than 40 years of age, other family members with early heart disease, postmenopausal female).

• Do not use this medicine right before or after heart bypass surgery.

• This medicine may increase the risk of ulcer or bleeding from the stomach or intestines. Talk with healthcare provider.

• This medicine does not mix well with some medicines. Serious reactions may occur. Check all medicines with healthcare provider.

• Please read the medication guide.

• If you have an allergy to oxycodone, ibuprofen, or any other part of this medicine.

• Tell healthcare provider if you are allergic to any medicine. Make sure to tell about the allergy and how it affected you. This includes telling about rash; hives; itching; shortness of breath; wheezing; cough; swelling of face, lips, tongue, or throat; or any other symptoms involved.

• If you have any of the following conditions: Asthma, intestinal blockage, or lung disease.

• If you are more than 24 weeks pregnant.

• If you are breast-feeding.

• Oxycodone binds to brain receptors, relieving pain. It decreases the feeling of pain and a person's response to pain.

• Ibuprofen blocks production and release of chemicals that cause pain and inflammation.

• Take this medicine with or without food. Take with food if it causes an upset stomach.

• Drink plenty of noncaffeine-containing liquid unless told to drink less liquid by healthcare provider.

• Take a missed dose as soon as possible.

• If it is almost time for the next dose, skip the missed dose and return to your regular schedule.

• Do not take a double dose or extra doses.

• Many times this medicine is taken on an as needed basis.

• Change in condition being treated. Is it better, worse, or about the same?

• Keep a diary of pain control.

• Bowel movements.

• Store at room temperature.

• Protect from moisture. Do not store in a bathroom or kitchen.

• If you have a life-threatening allergy, wear allergy identification at all times.

• Do not share your medicine with others and do not take anyone else's medicine.

• Keep all medicine out of the reach of children and pets.

• Most medicines can be thrown away in household trash after mixing with coffee grounds or kitty litter and sealing in a plastic bag.

• Keep a list of all your medicines (prescription, natural products, supplements, vitamins, over-the-counter) with you. Give this list to healthcare provider (doctor, nurse, nurse practitioner, pharmacist, physician assistant).

• Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088 or in Canada to Health Canada's Canada Vigilance Program at 1-866-234-2345.

• Talk with healthcare provider before starting any new medicine, including over-the-counter, natural products, or vitamins.

Created: 2006-10-13 14:48:29.0

Modified: 2010-03-22 14:15:22.0

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