Osteoarthritis and Nonsteroidal Anti-inflammatory Agents (NSAIDs)

Nonsteroidal anti-inflammatory drugs (NSAIDs) help decrease inflammation, swelling, and joint pain which are the major symptoms of osteoarthritis. Many NSAIDs are available over-the-counter. You may be given a prescription for a higher dose. Topical pain medications (eg, creams, patches) are another option.

The following are among the most common examples for NSAIDs prescribed for the treatment of Osteoarthritis.

• Naproxen (Naprosyn, Anaprox, Aleve)
• Ketoprofen (Orudis)
• Ibuprofen (Motrin, Advil, Nuprin)
• Indomethacin (Indocin)
• Sulindac (Clinoril)
• Meclofenamate (Meclomen)
• Ketorolac (Toradol)
• Piroxicam (Feldene)
• Diclofenac (Voltaren, Cataflam)

Read more details about Nonsteroidal Anti-inflammatory Agents (NSAIDs).

Drinking alcoholic beverages or taking other NSAIDs while you are already using an NSAID can increase your risk of side effects. Always take NSAIDs with food to decrease the chance of stomach irritation.

Possible side effects include:

• Stomach upset
• Stomach ulcers
• Kidney damage
• Liver inflammation
• Confusion, dizziness, lightheadedness
• Severe allergic reaction (hives, difficulty breathing, swelling around the eyes)
• Increased risk of bleeding – Always inform your healthcare providers that you are taking an NSAID before having any medical or dental procedures or surgeries.

Take special care with NSAIDs if you have had an ulcer or gastritis, as they can irritate these conditions. Tell your doctor if you have a stomach condition before you start taking any of these medications.

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