Tried or prescribed Cyclooxygenase-2 or COX-2 Inhibitors for Osteoarthritis? Share your experience.
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Effect of Cyclooxygenase-2 or COX-2 Inhibitors on Osteoarthritis
COX-2 inhibitors work in a way similar to NSAIDs, helping to decrease inflammation, swelling, and joint pain. In addition, they have the benefit of causing less stomach irritation. In particular, COX-2 inhibitors cause far fewer stomach ulcers than do NSAIDs.
Most commonly prescribed COX-2 Inhibitors for Osteoarthritis:
- Celecoxib (Celebrex)
- Meloxicam (Mobic)
Read more details about Cyclooxygenase-2 or COX-2 Inhibitors.
Drinking alcoholic beverages or taking NSAIDs while you are using a COX-2 inhibitor can increase your risk of side effects.
Possible side effects include:
- Liver inflammation
- Confusion
- Severe allergic reaction ( hives, difficulty breathing, swelling around the eyes)
- Stomach upset
- Heart attack
- Stroke
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3/17/2007 http://www.ebscohost.com/dynamed/what.php : Yelland MJ, Nickles CJ, McNairn N, Del Mar CB, Schluter PJ, Brown RM. Celecoxib compared with sustained-release paracetamol for osteoarthritis: a series of n-of-1 trials. Rheumatology (Oxford). 2007;46:135-140. Epub 2006 Jun.
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