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Safety Issues
Because nettle leaf has a long history of food use, it is believed to be safe.
Nettle root does not have as extensive a history to go by. Although detailed safety studies have not been reported, no significant adverse effects have been noted in Germany where nettle root is widely used. In practice, it is nearly side-effect free. In one study of 4,087 people who took 600 to 1,200 mg of nettle root daily for 6 months, less than 1% reported mild gastrointestinal distress and only 0.19% experienced allergic reactions (skin rash). 1 For theoretical reasons, there are some concerns that nettle may interact with diabetes, blood pressure, anti-inflammatory, and sedative medications, although there are no reports of any problems occurring. 2 The safety of nettle root or leaf for pregnant or nursing mothers has not been established, and there are concerns based on animal studies and its traditional use for inducing abortions. 3 However, nettle leaf tea is a traditional drink for pregnant and nursing women.
Interactions You Should Know About
If you are taking:
- Anti-inflammatory, antihypertensive, sedative, or blood sugar-lowering medications: Nettle might conceivably interact with them, although this is unlikely.
References
- Shulz V, Hansel R, Tyler VE. Rational Phytotherapy: A Physicians' Guide to Herbal Medicine. 3rd ed. Berlin, Germany: Springer-Verlag; 1998:229.
- Newall CA, Anderson LA, Phillipson JD. Herbal Medicines: A Guide for Health-Care Professionals. London, England: Pharmaceutical Press; 1996:201-202.
- Schöttner M, Gansser D, Spiteller G. Lignans from the roots of Urtica dioica and their metabolites bind to human sex hormone binding globulin (SHBG). Planta Med. 63(6):529-32.