Methylprednisolone Side Effects and Warnings

What are the precautions when taking this medicine?

• If you have been taking this medicine for several weeks, talk with healthcare provider before stopping. You may want to gradually withdraw this medicine.

• Wear disease medical alert identification.

• Talk with healthcare provider before receiving any vaccinations. Use with this medicine may either increase the risk of serious infection or make the vaccination less effective.

• Do not run out of this medicine.

• Avoid exposure to chickenpox and measles.

• Do not take antacids within 2 hours of this medicine.

• If you have diabetes, talk with healthcare provider. This medicine can increase blood sugar.

• If you have glaucoma or cataracts, talk with healthcare provider.

• If you have high blood pressure, talk with healthcare provider.

• If you have osteoporosis, talk with healthcare provider.

• If you have stomach ulcers, talk with healthcare provider.

• If you have tuberculosis, talk with healthcare provider.

• If you have a weakened heart, talk with healthcare provider.

• Tell dentists, surgeons, and other healthcare providers that you use this medicine.

• Check medicines with healthcare provider. This medicine may not mix well with other medicines.

• Avoid alcohol (includes wine, beer, and liquor).

• Tell healthcare provider if you are pregnant or plan on getting pregnant.

• Tell healthcare provider if you are breast-feeding.

What are some possible side effects of this medicine?

• High blood sugar. Usually reverses when stopped.

• Risk of infection. Avoid people with infections, colds, or flu.

• Belly pain.

• Nausea or vomiting. Small frequent meals, frequent mouth care, sucking hard, sugar-free candy, or chewing sugar-free gum may help.

• Weight gain.

• Mood changes.

• Change in body fat distribution.

• Weakened bones with long-term use.

• Muscle weakness.

• Skin changes (acne, stretch marks, slow healing, hair growth).

• Cataracts or glaucoma with long-term use.

• For females, vaginal yeast infection. Report itching or discharge.

Reasons to call healthcare provider immediately

• If you suspect an overdose, call your local poison control center or emergency department immediately.

• Signs of a life-threatening reaction. These include wheezing; chest tightness; fever; itching; bad cough; blue skin color; fits; or swelling of face, lips, tongue, or throat.

• Signs or symptoms of infection. These include a fever of 100.5 degrees or higher, chills, severe sore throat, ear or sinus pain, cough, increased sputum or change in color, painful urination, mouth sores, wound that will not heal, or anal itching or pain.

• Feeling extremely tired, weak, or irritable; trembling; having a fast heartbeat, confusion, sweating, or dizziness if you missed a dose or recently stopped this medicine.

• Difficulty breathing.

• Significant weight gain.

• Severe nausea or vomiting.

• Sudden change in vision.

• If exposure to chickenpox has occurred and you have not had chickenpox or been vaccinated against it.

• Any rash.

• No improvement in condition or feeling worse.