Inosine Side Effects and Warnings

Safety Issues

Although no side effects have been reported with the use of inosine, long-term use should be avoided. A very preliminary double-blind crossover study that enrolled 7 participants suggests that high doses of inosine (5,000 to 10,000 mg per day for 5 to 10 days) may increase the risk of uric acid–related problems, such as gout or kidney stones. ¹ The safety of inosine for young children, pregnant or nursing women, or those with serious liver or kidney disease has not been established.

As with all supplements taken in multigram doses, it is important to purchase a reputable product, because a contaminant present even in small percentages could add up to a real problem.