Hydrocodone and Acetaminophen Side Effects and Warnings

What are the precautions when taking this medicine?

• This medicine may be habit-forming with long-term use.

• Avoid other sources of acetaminophen. An overdose may cause dangerous problems.

• If you are 65 or older, use this medicine with caution. You could have more side effects.

• If you have lung disease, talk with healthcare provider. You may be more sensitive to this medicine.

• Check medicines with healthcare provider. This medicine may not mix well with other medicines.

• Avoid medicines and natural products that slow your actions and reactions. These include sedatives, tranquilizers, mood stabilizers, antihistamines, and other pain medicine.

• Avoid or limit alcohol intake (includes wine, beer, and liquor) to less than 3 drinks a day. Drinking too much alcohol may increase the risk of liver disease.

• You may not be alert. Avoid driving, doing other tasks or activities until you see how this medicine affects you.

• Be careful if you have G6PD deficiency. Anemia may occur.

• Tell healthcare provider if you are pregnant or plan on getting pregnant.

What are some possible side effects of this medicine?

• Feeling lightheaded, sleepy, having blurred vision, or a change in thinking clearly. Avoid driving, doing other tasks or activities that require you to be alert or have clear vision until you see how this medicine affects you.

• Nausea or vomiting. Small frequent meals, frequent mouth care, sucking hard, sugar-free candy, or chewing sugar-free gum may help.

• Constipation. More liquids, regular exercise, or a fiber-containing diet may help. Talk with healthcare provider about a stool softener or laxative.

• Liver damage can rarely occur.

Reasons to call healthcare provider immediately

• If you suspect an overdose, call your local poison control center or emergency department immediately.

• Signs of a life-threatening reaction. These include wheezing; chest tightness; fever; itching; bad cough; blue skin color; fits; or swelling of face, lips, tongue, or throat.

• Severe dizziness or passing out.

• Difficulty breathing.

• Significant change in thinking clearly and logically.

• Poor pain control.

• Severe nausea or vomiting.

• Severe constipation.

• Feeling extremely tired or weak.

• Yellow skin or eyes.

• Not able to eat.

• Any rash.

• No improvement in condition or feeling worse.