Hyaluronate and Derivatives Side Effects and Warnings

What are the precautions when taking this medicine?

All forms:

• Check medicines with healthcare provider. This medicine may not mix well with other medicines.

• Tell healthcare provider if you are pregnant or plan on getting pregnant.

• Tell healthcare provider if you are breast-feeding.

Knee:

• Avoid activity for 48 hours or as directed by healthcare provider.

Skin injection:

• Talk with healthcare provider before using other: aspirin, aspirin-containing products, blood thinners, garlic, ginseng, ginkgo, ibuprofen or like products, pain medicines, or vitamin E.

• Avoid sun, sunlamps, and tanning beds until swelling is gone.

• Avoid exposure to cold weather until swelling is gone.

What are some possible side effects of this medicine?

• Feeling lightheaded, sleepy, having blurred vision, or a change in thinking clearly. Avoid driving, doing other tasks or activities that require you to be alert or have clear vision until you see how this medicine affects you.

• Headache.

• Bruising.

• Swelling.

Eye:

• Eye irritation.

• Increased eye pressure.

Knee, Skin injection:

• Irritation where the shot is given.

Topical:

• Skin irritation.

Reasons to call healthcare provider immediately

• If you suspect an overdose, call your local poison control center or emergency department immediately.

• Signs of a life-threatening reaction. These include wheezing; chest tightness; fever; itching; bad cough; blue skin color; fits; or swelling of face, lips, tongue, or throat.

• Difficulty breathing.

• Severe swelling.

• Severe belly pain.

• Chest pain or pressure, fast heartbeat, or passing out.

• Severe skin irritation.

• Sudden change in vision, eye pain, or irritation.

• Any rash.

• No improvement in condition or feeling worse.