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Safety Issues
As a widely used beverage tea, hibiscus is presumed to have a high degree of safety. However, comprehensive safety testing has not been performed. Maximum safe doses in pregnant or nursing women, young children, or individuals with severe liver or kidney disease have not been established.
Some evidence suggests that hibiscus might slightly alter the metabolism of the drug acetaminophen, though the effect is probably not large enough to be very important. 1
References
- Kolawole JA, Maduenyi A. Effect of zobo drink ( Hibiscus sabdariffa water extract) on the pharmacokinetics of acetaminophen in human volunteers. Eur J Drug Metab Pharmacokinet. 2004;29:25–9