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What Is Guggul Used for Today?
Based on preliminary studies, guggul has become a popular herbal treatment for high cholesterol . 1 2 3 However, the best-designed trial failed to find benefit.
Other potential uses of guggul have no more than minimal supporting evidence. One small study hints that guggul might be helpful for acne . 4 In addition, a study in mice found potential anti-diabetic effects. 5 Recently, guggul has been promoted as a weight-loss agent. Supposedly, it works by enhancing thyroid function. However, there is little evidence that guggul actually affects the thyroid, and one small double-blind, placebo-controlled trial failed to find it effective for weight loss. 6
References
- Nityanand S, Srivastava JS, Asthana OP. Clinical trials with gugulipid. A new hypolipidaemic agent. J Assoc Physicians India. 37(5):323-8.
- Agarwal RC, Singh SP, Saran RK, et al. Clinical trial of gugulipid—a new hyperlipidemic agent of plant origin in primary hyperlipidemia. Indian J Med Res. 1986;84:626-634.
- Singh RB, Niaz MA, Ghosh S. Hypolipidemic and antioxidant effects of Commiphora mukul as an adjunct to dietary therapy in patients with hypercholesterolemia. Cardiovasc Drugs Ther. 1994;8:659-664.
- Thappa DM, Dogra J. Nodulocystic acne: oral gugulipid versus tetracycline. J Dermatol. 21(10):729-31.
- Subramaniam A, Stocker C, Sennitt MV, et al. Guggul lipid reduces insulin resistance and body weight gain in C57B1/6 lep/lep mice [abstract]. Int J Obes Relat Metab Disord. 2001;25(suppl 2):S24.
- Antonio J, Colker CM, Torina GC, et al. Effects of a standardized guggulsterone phosphate supplement on body composition in overweight adults: a pilot study. Curr Ther Res. 1999;60:220-227.
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