Tried or prescribed Glyburide and Metformin? Share your experience.
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(GLYE byoor ide & met FOR min)
U.S. Brand Names
Glucovance®
Mexican Brand Names
Bi-Euglucon M "5"
Pharmacologic Category
Antidiabetic Agent, Biguanide; Antidiabetic Agent, Sulfonylurea
What key warnings should I know about before taking this medicine?
• A small number of people may develop an acidity to their blood. Metformin can cause this. It may occur in people whose liver or kidneys do not work normally.
• This medicine does not mix well with some medicines. Serious reactions may occur. Check all medicines with healthcare provider.
Reasons not to take this medicine
• If you have an allergy to glyburide, metformin, or any other part of this medicine.
• Tell healthcare provider if you are allergic to any medicine. Make sure to tell about the allergy and how it affected you. This includes telling about rash; hives; itching; shortness of breath; wheezing; cough; swelling of face, lips, tongue, or throat; or any other symptoms involved.
• If you have a sulfonamide ("sulfa") allergy, talk with healthcare provider.
• If you have any of the following conditions: Acidic blood condition, dehydration, drink alcohol to excess, kidney disease, or liver disease.
• If you are having an x-ray with dye.
How does it work?
• Glyburide increases insulin secretion from the pancreas and may make tissues more responsive to insulin.
• Metformin reduces sugar production and helps insulin work better.
How is it best taken?
• This medicine can be used alone or in combination with other diabetes medicine.
• Take this medicine with food.
• Follow diet plan and exercise program as recommended by healthcare provider.
What do I do if I miss a dose? (does not apply to patients in the hospital)
• Take a missed dose as soon as possible.
• If it is almost time for the next dose, skip the missed dose and return to your regular schedule.
• Do not take a double dose or extra doses.
• Do not change dose or stop medicine. Talk with healthcare provider.
What should I monitor?
• Change in condition being treated. Is it better, worse, or about the same?
• Check blood sugar as directed by healthcare provider.
• Check blood work (kidney and liver function). Talk with healthcare provider.
• Have a yearly eye exam and visit to the foot doctor.
How should I store this medicine?
• Store at room temperature.
• Protect from moisture. Do not store in a bathroom or kitchen.
General statements
• If you have a life-threatening allergy, wear allergy identification at all times.
• Do not share your medicine with others and do not take anyone else's medicine.
• Keep all medicine out of the reach of children and pets.
• Most medicines can be thrown away in household trash after mixing with coffee grounds or kitty litter and sealing in a plastic bag.
• Keep a list of all your medicines (prescription, natural products, supplements, vitamins, over-the-counter) with you. Give this list to healthcare provider (doctor, nurse, nurse practitioner, pharmacist, physician assistant).
• Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088 or in Canada to Health Canada's Canada Vigilance Program at 1-866-234-2345.
• Talk with healthcare provider before starting any new medicine, including over-the-counter, natural products, or vitamins.
Created: 2005-04-07 16:45:41.0
Modified: 2010-03-09 08:25:00.0
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