Everolimus Side Effects and Warnings

What are the precautions when taking this medicine?

• There is a risk of skin cancer. Avoid sun, sunlamps, and tanning beds. Use sunscreen; wear protective clothing and eyewear.

• The risk of cancer is higher after using this medicine.

• If you have diabetes, talk with healthcare provider.

• If you have high cholesterol, talk with healthcare provider.

• If you have liver disease, talk with healthcare provider.

• Tell dentists, surgeons, and other healthcare providers that you use this medicine.

• Check medicines with healthcare provider. This medicine may not mix well with other medicines.

• Do not take St John's wort with this medicine. It may make this medicine less effective.

• Avoid grapefruit and grapefruit juice.

• Talk with healthcare provider before receiving any vaccinations. Use with this medicine may either increase the risk of serious infection or make the vaccination less effective.

• Use birth control that you can trust, during treatment, and for 2 months after treatment ends.

What are some possible side effects of this medicine?

• Risk of infection. Avoid people with infections, colds, or flu.

• Anemia, low white blood cell count, and low platelet count.

• High cholesterol level.

• High blood sugar. Usually reverses when stopped.

• High blood pressure.

• Swelling.

• Feeling tired or weak.

• Fever.

• Headache.

• Nausea or vomiting. Small frequent meals, frequent mouth care, sucking hard, sugar-free candy, or chewing sugar-free gum may help.

• Mouth irritation. Frequent mouth care with a soft toothbrush or cotton swabs and rinsing mouth may help.

• Diarrhea.

• Not hungry.

• Lung damage can rarely occur.

Reasons to call healthcare provider immediately

• If you suspect an overdose, call your local poison control center or emergency department immediately.

• Signs of a life-threatening reaction. These include wheezing; chest tightness; fever; itching; bad cough; blue skin color; fits; or swelling of face, lips, tongue, or throat.

• Signs or symptoms of infection. These include a fever of 100.5 degrees or higher, chills, severe sore throat, ear or sinus pain, cough, increased sputum or change in color, painful urination, mouth sores, wound that will not heal, or anal itching or pain.

• Difficulty breathing.

• Severe belly pain.

• Severe nausea or vomiting.

• Severe diarrhea.

• Unusual bruising or bleeding.

• Severe mouth irritation.

• Severe back pain.

• Blood in the urine.

• Unable to pass urine.

• Skin wound that will not heal.

• Any rash.

• No improvement in condition or feeling worse.