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What Is Elderberry Used for Today?
A product containing elderberry, as well as small amounts of echinacea and bee propolis , has been widely marketed as a cold and flu remedy. Weak evidence suggests that this mixture may stimulate the immune system and also inhibit viral growth. 1 In a preliminary double-blind study, this mixture was found to reduce symptoms and speed recovery from influenza A, the type of influenza for which flu shots are given. 2 A few of the participants in this study had influenza B (a milder form of influenza), and the elderberry mixture appeared to be helpful for them as well. Another preliminary double-blind study evaluated people with influenza B, and also found benefit. 3
Elderberry has also shown some preliminary promise for use in other viral infections, including HIV 4 and herpes . 5 Based on promising results in an uncontrolled study, researchers performed a small double-blind, placebo-controlled study on the potential benefits of elderberry for improving cholesterol levels. 6 Unfortunately, at the dose used, no benefits were evident.
References
- Barak V, Halperin T, Kalickman I. The effect of Sambucol, a black elderberry-based, natural product, on the production of human cytokines: I. Inflammatory cytokines. Eur Cytokine Netw. 12(2):290-6.
- Zakay-Rones Z., Thom E., Wollan T., et al. Randomized study of the efficacy and safety of oral elderberry extract in the treatment of influenza A and B virus infections. Journal of International Medical Research. 2004;32:132-140.
- Zakay-Rones Z, Varsano N, Zlotnik M, et al. Inhibition of several strains of influenza virus in vitro and reduction of symptoms by an elderberry extract ( Sambucus nigra L.) during an outbreak of influenza B Panama. J Altern Complement Med. 1995;1:361–369.
- Shapira-Nahor B. The effect of Sambucol on HIV infection in vitro. Annual Israel Congress of Microbiology, February 6–7, 1995.
- Morag A, Mumcuoglu M, Baybikov T, et al. Inhibition of sensitive and acyclovir-resistant HSV-1 strains by an elderberry extract in vitro [abstract]. Phylotherapie. 1997;25:97–98.
- Murkovic M, Abuja PM, Bergmann AR, Zirngast A, Adam U, Winklhofer-Roob BM, Toplak H. Effects of elderberry juice on fasting and postprandial serum lipids and low-density lipoprotein oxidation in healthy volunteers: a randomized, double-blind, placebo-controlled study. Eur J Clin Nutr. 58(2):244-9.
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