Possible side effects include:
Originally created and prescribed for the treatment of Depression,
Tricyclics are a form of antidepressants that are sometimes also used to treat chronic fatigue syndrome, especially to help improve sleep, relieve a depressed mind and general pain. If improvement is seen, it usually takes between 2 and 6 weeks to see results.
Common names include for
Tricyclic antidepressants regulate the neurotransmitters serotonin and/or noradrenalin in the brain. They are at times prescribed to help treat anxiety disorders, including panic disorders, though were originally created as a treatment for depression.
Common names include:
Tricyclic antidepressants regulate the neurotransmitters serotonin and/or noradrenalin in the brain. They are at times prescribed to help treat anxiety disorders, including panic disorders, though were originally created as a treatment for depression.
Common names include:
Tricyclic antidepressants regulate the neurotransmitters serotonin and/or noradrenalin in the brain. They are at times prescribed to help treat anxiety disorders, including panic disorders, though were originally created as a treatment for depression The majority of the TCAs are thought to act primarily as serotonin-norepinephrine reuptake inhibitors (SNRIs) by blocking the serotonin transporter (SERT) and the norepinephrine transporter (NET) which results in an elevation in concentration of these neurotransmitters. By increasing the concentration of these calming neurotransmitters, the person subsequently might become more calm, less anxious, and possibly, less likely to suffer from a panic attack or panic disorder.
TCAs have also been linked to sudden death syndrome in children. For this reason, many clinicians put them at the bottom of the list of ADHD medications for children. TCAs can also be risky for substance abusers. Before starting TCA treatment for children, doctors recommend getting a baseline EKG in addition to monitoring side effects.
Side effects
The side effect associated with Tricyclic antidepressants are usually mild. These may include:
To reduce the risk of side effects, your doctor will prescribe a low starting dose and slowly increase the amount. Tricyclics are generally well-tolerated especially in low doses. The doses needed to induce pain relief are typically lower than the doses recommended for treating depression
All of the Tricyclics have the same side effects, but in varying degrees. To fully understand these potential side effects, they are grouped as follows:
The majority of the TCAs are thought to act primarily as serotonin-norepinephrine reuptake inhibitors (SNRIs) by blocking the serotonin transporter (SERT) and the norepinephrine transporter (NET) which results in an elevation in concentration of these neurotransmitters. By increasing the concentration of these calming neurotransmitters, the person subsequently might become more calm, less anxious, and possibly, less likely to suffer from a panic attack or panic disorder.
Tricyclic antidepressants regulate the neurotransmitters serotonin and/or noradrenalin in the brain. They are at times prescribed to help treat anxiety disorders, including panic disorders, though were originally created as a treatment for depression.
Common names include:
The majority of the TCAs are thought to act primarily as serotonin-norepinephrine reuptake inhibitors (SNRIs) by blocking the serotonin transporter (SERT) and the norepinephrine transporter (NET) which results in an elevation in concentration of these neurotransmitters. By increasing the concentration of these calming neurotransmitters, the person subsequently might become more calm, less anxious, and possibly, less likely to suffer from a panic attack or panic disorder.
Created as a treatment for depression, Tricyclics have sometimes been prescribed for GAD as well. Common names of Tricyclics include:
Tricyclic antidepressants are thought to regulate serotonin and norepinephrine in the brain. Thus, they have been used effectively for the treatment of depression. Serotonin is a neurotransmitter with calming effects, and oftentimes people with anxiety do not have adequate amounts of serotonin. Thus, tricyclics can help in regulating levels of serotonin.
These drugs are highly toxic if taken in large doses; therefore, they are often not prescribed for suicidal patients. Tricyclic antidepressants are not addictive. These drugs are infrequently used for the treatment of GAD because of the many side effects, plus the overdose potential.
Common names include:
Tricyclic antidepressants are thought to regulate serotonin and norepinephrine in the brain. Thus, they have been used effectively for the treatment of depression. Serotonin is a neurotransmitter with calming effects, and oftentimes people with anxiety do not have adequate amounts of serotonin. Thus, tricyclics can help in regulating levels of serotonin.
These drugs are highly toxic if taken in large doses; therefore, they are often not prescribed for suicidal patients. Tricyclic antidepressants are not addictive. These drugs are infrequently used for the treatment of GAD because of the many side effects, plus the overdose potential.
For many years, tricyclic antidepressants (TCAs) and heterocyclics were the main depression medications used in the treatment of severe depression. The tricyclics are considered "dirty" drugs because they react with a number of receptors besides the one responsible for their therapeutic effect, resulting in a host of side effects. In terms of chemical structure, secondary amine drugs such as amoxapine, desipramine, maprotiline, nortriptyline, and protriptyline are preferred to tertiary amine drugs because they have fewer side effects.
For many years, tricyclic antidepressants (TCAs) and heterocyclics were the main depression medications used in the treatment of severe depression. The tricyclics are considered "dirty" drugs because they react with a number of receptors besides the one responsible for their therapeutic effect, resulting in a host of side effects. In terms of chemical structure, secondary amine drugs such as amoxapine, desipramine, maprotiline, nortriptyline, and protriptyline are preferred to tertiary amine drugs because they have fewer side effects.
For many years, tricyclic antidepressants (TCAs) and heterocyclics were the main depression medications used in the treatment of severe depression. The tricyclics are considered "dirty" drugs because they react with a number of receptors besides the one responsible for their therapeutic effect, resulting in a host of side effects. In terms of chemical structure, secondary amine drugs such as amoxapine, desipramine, maprotiline, nortriptyline, and protriptyline are preferred to tertiary amine drugs because they have fewer side effects.
For many years, tricyclic antidepressants (TCAs) and heterocyclics were the main depression medications used in the treatment of severe depression. The tricyclics are considered "dirty" drugs because they react with a number of receptors besides the one responsible for their therapeutic effect, resulting in a host of side effects. In terms of chemical structure, secondary amine drugs such as amoxapine, desipramine, maprotiline, nortriptyline, and protriptyline are preferred to tertiary amine drugs because they have fewer side effects.
A psychiatrist will typically prescribe these brands of drugs for patients with certain types of depression.3
| Drug name and brand name | Starting dose | Therapeutic dose |
| Amitriptyline (Elavil) | 25-50 mg | 150-300 |
| Doxepin (Sinequan, Adapin) | 25-50 mg | 150-300 mg |
| *Imipramine (Tofranil) | 25-50 mg | 150-300 mg |
| Trimipramine (Surmontil) | 25-50 mg | 100-300 mg |
| Clomipramine (Anafranil) | 25-50mg | 150-200 mg |
| Amoxapine (Asendin) | 25-50 mg | 150-400 mg |
| Desipramine (Norpramin) | 25-50 mg | 150-300 mg |
| Maprotiline (Ludiomil) | 25-50 mg | 150-225 mg |
| Nortriptyline (Aventyl, Pamelor) | 10-25 mg | 75-125 mg |
| Protriptyline (Vivactil) | 5-15 mg | 15-40 mg |
| **Trazodone (Desyrel) | 25-50 mg | 150-400 mg |
*One of the first TCAs, Gold standard TCA antidepressant
** Of the existing tricyclics, trazodone appears to have the lowest degree of cardiotoxicity
A psychiatrist will typically prescribe these brands of drugs for patients with certain types of depression.3
| Drug name and brand name | Starting dose | Therapeutic dose |
| Amitriptyline (Elavil) | 25-50 mg | 150-300 |
| Doxepin (Sinequan, Adapin) | 25-50 mg | 150-300 mg |
| *Imipramine (Tofranil) | 25-50 mg | 150-300 mg |
| Trimipramine (Surmontil) | 25-50 mg | 100-300 mg |
| Clomipramine (Anafranil) | 25-50mg | 150-200 mg |
| Amoxapine (Asendin) | 25-50 mg | 150-400 mg |
| Desipramine (Norpramin) | 25-50 mg | 150-300 mg |
| Maprotiline (Ludiomil) | 25-50 mg | 150-225 mg |
| Nortriptyline (Aventyl, Pamelor) | 10-25 mg | 75-125 mg |
| Protriptyline (Vivactil) | 5-15 mg | 15-40 mg |
| **Trazodone (Desyrel) | 25-50 mg | 150-400 mg |
*One of the first TCAs, Gold standard TCA antidepressant
** Of the existing tricyclics, trazodone appears to have the lowest degree of cardiotoxicity
A psychiatrist will typically prescribe these brands of drugs for patients with certain types of depression.3
| Drug name and brand name | Starting dose | Therapeutic dose |
| Amitriptyline (Elavil) | 25-50 mg | 150-300 |
| Doxepin (Sinequan, Adapin) | 25-50 mg | 150-300 mg |
| *Imipramine (Tofranil) | 25-50 mg | 150-300 mg |
| Trimipramine (Surmontil) | 25-50 mg | 100-300 mg |
| Clomipramine (Anafranil) | 25-50mg | 150-200 mg |
| Amoxapine (Asendin) | 25-50 mg | 150-400 mg |
| Desipramine (Norpramin) | 25-50 mg | 150-300 mg |
| Maprotiline (Ludiomil) | 25-50 mg | 150-225 mg |
| Nortriptyline (Aventyl, Pamelor) | 10-25 mg | 75-125 mg |
| Protriptyline (Vivactil) | 5-15 mg | 15-40 mg |
| **Trazodone (Desyrel) | 25-50 mg | 150-400 mg |
*One of the first TCAs, Gold standard TCA antidepressant
** Of the existing tricyclics, trazodone appears to have the lowest degree of cardiotoxicity
A psychiatrist will typically prescribe these brands of drugs for patients with certain types of depression.3
| Drug name and brand name | Starting dose | Therapeutic dose |
| Amitriptyline (Elavil) | 25-50 mg | 150-300 |
| Doxepin (Sinequan, Adapin) | 25-50 mg | 150-300 mg |
| *Imipramine (Tofranil) | 25-50 mg | 150-300 mg |
| Trimipramine (Surmontil) | 25-50 mg | 100-300 mg |
| Clomipramine (Anafranil) | 25-50mg | 150-200 mg |
| Amoxapine (Asendin) | 25-50 mg | 150-400 mg |
| Desipramine (Norpramin) | 25-50 mg | 150-300 mg |
| Maprotiline (Ludiomil) | 25-50 mg | 150-225 mg |
| Nortriptyline (Aventyl, Pamelor) | 10-25 mg | 75-125 mg |
| Protriptyline (Vivactil) | 5-15 mg | 15-40 mg |
| **Trazodone (Desyrel) | 25-50 mg | 150-400 mg |
*One of the first TCAs, Gold standard TCA antidepressant
** Of the existing tricyclics, trazodone appears to have the lowest degree of cardiotoxicity
