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Ginseng Contributions by sshowalter

Article Revisions

  1. See DM, Broumand N, Sahl L, et al. In vitro effects of echinacea and ginseng on natural killer and antibody-dependent cell cytotoxicity in healthy subjects and chronic fatigue syndrome or acquired immunodeficiency patients. Immunopharmacology. 1997;35:229-235.
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A test tube study of echinacea and Panax ginseng found that both increased cellular immune function in cells taken from people with chronic fatigue syndrome.20 However, many herbs and supplements can cause measurable changes in immune function, and such observations do not prove that there will be an actual benefit in people with the disease.

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Though not yet tested in isolation, panax ginseng along with echinacea might be helpful in treating chronic fatigue syndrome.

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Edited Ginseng Overview: Overview 14 years ago

There are three different herbs commonly called ginseng: Asian or Korean ginseng (Panax ginseng), American ginseng (Panax quinquefolius), and Siberian “ginseng” ( Eleutherococcus senticosus ). The latter herb is actually not ginseng at all and is discussed in a separate article .

Asian ginseng is a perennial herb with a taproot resembling the shape of the human body. It grows in northern China, Korea, and Russia; its close relative, Panax quinquefolius, is cultivated in the United States. Because ginseng must be grown for 5 years before it is harvested, it commands a high price, with top-quality roots easily selling for more than $10,000. Dried, unprocessed ginseng root is called white ginseng, and steamed, heat-dried root is red ginseng. Chinese herbalists believe that each form has its own particular benefits.

Ginseng is widely regarded by the public as a stimulant. According to everyone who uses it seriously, though, that isn't the right description. In traditional Chinese herbology, Panax ginsengwas used to strengthen the digestion and the lungs, calm the spirit, and increase overall energy. When the Russian scientist Israel I. Brekhman became interested in the herb prior to World War II, he came up with a new idea about ginseng: He decided that it was an adaptogen .

The term adaptogen refers to a hypothetical treatment described as follows: An adaptogen should help the body adapt to stresses of various kinds, whether heat, cold, exertion, trauma, sleep deprivation, toxic exposure, radiation, infection, or psychological stress. Furthermore, an adaptogen should cause no side effects, be effective in treating a wide variety of illnesses, and help return an organism toward balance no matter what may have gone wrong.

Perhaps the only indisputable example of an adaptogen is a healthful lifestyle. By eating right, exercising regularly, and generally living a life of balance and moderation, you will increase your physical fitness and ability to resist illnesses of all types. Whether there are any substances that can do as much remains unclear. However, Brekhman felt certain that ginseng produced similarly universal benefits.

Interestingly, traditional Chinese medicine (where ginseng comes from) does not entirely agree. There is no one-size-fits-all in Chinese medical theory. Like any other herb, ginseng is said to be helpful for those people who need its particular effects, and neutral or harmful for others. But in Europe, Brekhman's concept has taken hold, and ginseng is widely believed to be a universal adaptogen.

... (more)
Edited Ginseng Overview: Overview 14 years ago

There are three different herbs commonly called ginseng: Asian or Korean ginseng (Panax ginseng), American ginseng (Panax quinquefolius), and Siberian “ginseng” ( Eleutherococcus senticosus ). The latter herb is actually not ginseng at all and is discussed in a separate article .

Asian ginseng is a perennial herb with a taproot resembling the shape of the human body. It grows in northern China, Korea, and Russia; its close relative, Panax quinquefolius, is cultivated in the United States. Because ginseng must be grown for 5 years before it is harvested, it commands a high price, with top-quality roots easily selling for more than $10,000. Dried, unprocessed ginseng root is called white ginseng, and steamed, heat-dried root is red ginseng. Chinese herbalists believe that each form has its own particular benefits.

Ginseng is widely regarded by the public as a stimulant. According to everyone who uses it seriously, though, that isn't the right description. In traditional Chinese herbology, Panax ginsengwas used to strengthen the digestion and the lungs, calm the spirit, and increase overall energy. When the Russian scientist Israel I. Brekhman became interested in the herb prior to World War II, he came up with a new idea about ginseng: He decided that it was an adaptogen .

The term adaptogen refers to a hypothetical treatment described as follows: An adaptogen should help the body adapt to stresses of various kinds, whether heat, cold, exertion, trauma, sleep deprivation, toxic exposure, radiation, infection, or psychological stress. Furthermore, an adaptogen should cause no side effects, be effective in treating a wide variety of illnesses, and help return an organism toward balance no matter what may have gone wrong.

Perhaps the only indisputable example of an adaptogen is a healthful lifestyle. By eating right, exercising regularly, and generally living a life of balance and moderation, you will increase your physical fitness and ability to resist illnesses of all types. Whether there are any substances that can do as much remains unclear. However, Brekhman felt certain that ginseng produced similarly universal benefits.

Interestingly, traditional Chinese medicine (where ginseng comes from) does not entirely agree. There is no one-size-fits-all in Chinese medical theory. Like any other herb, ginseng is said to be helpful for those people who need its particular effects, and neutral or harmful for others. But in Europe, Brekhman's concept has taken hold, and ginseng is widely believed to be a universal adaptogen.

... (more)

Safety Issues

Ginseng appears to be nontoxic, both in the short- and long-term, according to the results of studies in mice, rats, chickens, and dwarf pigs. 1 2 3 Reported side effects are rare. There are a few case reports of breast tenderness, postmenopausal vaginal bleeding, and menstrual abnormalities associated with Panax ginsenguse. 4 5 6 7 Such side effects suggest that it has estrogenic properties. However, a large double-blind trial of Panax ginsengfound no estrogen-like effects. 8 Another double-blind trial found no effects on estrogen or testosterone, 9 and a carefully designed test-tube study showed that ginseng is not estrogenic. 10 Therefore, it is possible that these apparent side effects were coincidental; another possibility is that adulterants in the ginseng product used caused the problem. Ginseng and other Asian herbal products have often been found to contain unlisted herbs and pharmaceuticals. 11 Estrogen itself stimulates the growth of breast cancer cells. Interestingly, in a test-tube study, Panax ginsengwas again found to be non-estrogenic, and yet it nonetheless stimulated the growth of breast cancer cells. 12 Although the mechanism of this effect is not known, the results suggest that women who have had breast cancer should avoid using ginseng.

Unconfirmed reports suggest that highly excessive doses of Panax ginsengcan cause insomnia, raise blood pressure, increase heart rate, and possibly cause other significant effects. Whether some of these cases were actually caused by caffeine mixed in with ginseng remains unclear. One double-blind study failed to find any effect on blood pressure. 13 One case report and one double-blind trial suggest that Panax ginsengcan reduce the anticoagulant effects of Coumadin (warfarin), 14 but another trial failed to find such an interaction. 15 The reason for this discrepancy is not clear, but prudence would nonetheless suggest not combining ginseng and warfarin.

Two reports indicate that combination treatment with Panax ginsengand antidepressant drugs may result in a manic episode. 16 There are also theoretical concerns regarding use of ginseng by people with diabetes. If it is true, as the preliminary studies discussed above suggest, that ginseng can in fact reduce blood sugar levels, people with diabetes who take ginseng might need to reduce their dose of medication. On the other hand, if certain types of ginseng have the opposite effect (as researchers hypothesize), this could necessitate an increase in medication. The bottom line: people with diabetes should only use ginseng under physician supervision.

In 1979, an article was published in the Journal of the American Medical Associationclaiming that people can become addicted to Panax ginsengand develop blood pressure elevations, nervousness, sleeplessness, diarrhea, and hypersexuality. 17 However, this report has since been thoroughly discredited and should no longer be taken seriously. 18 Chinese tradition suggests that Panax ginsengshould not be used by pregnant or nursing mothers, and one animal study hints that ginseng use by a pregnant mother could cause birth defects. 19 Safety in young children or people with severe liver or kidney disease has not been established.

Interactions You Should Know About

If you are taking:

  • Antidepressants: Panax ginsengmight cause manic episodes.
  • Insulin or oral hypoglycemics : Various forms of ginseng may unpredictably alter your dosage need.
  • Coumadin ( warfarin ): Panax ginsengmight possibly decrease its effect.
  • Influenza vaccine : Panax ginsengmight help it work better.
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  1. Fugh-Berman, Adriane (2000). "Herb-drug interactions". The Lancet 355 (9198): 134–138. doi:10.1016/S0140-6736(99)06457-0. ISSN 0140-6736.
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Edited Ginseng Overview: Overview 14 years ago

There are three different herbs commonly called ginseng: Asian or Korean ginseng (Panax ginseng), American ginseng (Panax quinquefolius), and Siberian “ginseng” ( Eleutherococcus senticosus ). The latter herb is actually not ginseng at all and is discussed in a separate article .

Asian ginseng is a slow-growingperennial perennial herb with a taproot resembling the shape of the human body. It grows in northern China, Korea, and Russia; its close relative, Panax quinquefolius, is cultivated in the United States. Because ginseng must be grown for 5 years before it is harvested, it commands a high price, with top-quality roots easily selling for more than $10,000. Dried, unprocessed ginseng root is called white ginseng, and steamed, heat-dried root is red ginseng. Chinese herbalists believe that each form has its own particular benefits.

Ginseng is widely regarded by the public as a stimulant. According to everyone who uses it seriously, though, that isn't the right description. In traditional Chinese herbology, Panax ginsengwas used to strengthen the digestion and the lungs, calm the spirit, and increase overall energy. When the Russian scientist Israel I. Brekhman became interested in the herb prior to World War II, he came up with a new idea about ginseng: He decided that it was an adaptogen .

The term adaptogen refers to a hypothetical treatment described as follows: An adaptogen should help the body adapt to stresses of various kinds, whether heat, cold, exertion, trauma, sleep deprivation, toxic exposure, radiation, infection, or psychological stress. Furthermore, an adaptogen should cause no side effects, be effective in treating a wide variety of illnesses, and help return an organism toward balance no matter what may have gone wrong.

Perhaps the only indisputable example of an adaptogen is a healthful lifestyle. By eating right, exercising regularly, and generally living a life of balance and moderation, you will increase your physical fitness and ability to resist illnesses of all types. Whether there are any substances that can do as much remains unclear. However, Brekhman felt certain that ginseng produced similarly universal benefits.

Interestingly, traditional Chinese medicine (where ginseng comes from) does not entirely agree. There is no one-size-fits-all in Chinese medical theory. Like any other herb, ginseng is said to be helpful for those people who need its particular effects, and neutral or harmful for others. But in Europe, Brekhman's concept has taken hold, and ginseng is widely believed to be a universal adaptogen.

... (more)