American Academy of Family Physicians website. Available at: http://www.aafp.org/online/en/home.html .
Guay AT, Spark RF, Bansal S, et al. American Association of Clinical Endocrinologists medical guidelines for clinical practice for the evaluation and treatment of male sexual dysfunction: a couple’s problem: 2003 update. Endocr Pract. 2003;9:77-95.
McMahon CN. Treating erectile dysfunction when PDE5 inhibitors fail. Brit Med J. 2006;332:589-592.
Montorsi F, Padma-Nathan H, Gilina S. Erectile function and assessments of erection hardness correlate positively with measures of emotional well-being, sexual satisfaction, and treatment satisfaction in men with erectile dysfunction treated with sildenafil citrate (Viagra). Urology. 2006;68:26-37.
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• Do not donate blood while using this medicine and for 1 month after stopping.
• Check medicines with healthcare provider. This medicine may not mix well with other medicines.
• Avoid alcohol (includes wine, beer, and liquor).
• To protect against sexually-transmitted diseases, use a latex condom.
• Muse®: Use a condom when having sex with a pregnant woman.
• Feeling dizzy. Rise slowly over several minutes from sitting or lying position. Be careful climbing.
• Headache.
• Penile pain.
• Irritation where the medicine is given.
• If you suspect an overdose, call your local poison control center or emergency department immediately.
• Signs of a life-threatening reaction. These include wheezing; chest tightness; fever; itching; bad cough; blue skin color; fits; or swelling of face, lips, tongue, or throat.
• Penile erection that lasts longer than 4 hours.
• Chest pain or pressure or fast heartbeat.
• Severe dizziness or passing out.
• Difficulty breathing.
• Severe penile pain.
• Unusual bruising or bleeding.
• Severe skin irritation.
• Any rash.
• No improvement in condition or feeling worse.
There are two types of alprostadil:
Alprostadil acts directly on the blood vessels in the penis to cause an erection. It can be inserted into the urethra (urinary tube in the penis) with a special device or injected with a small needle. Erection occurs in 8-10 minutes and lasts 30-60 minutes. The injection is effective in about 65%-85% of users; the insert is effective in about 65%. The maximal number of injections per week is three.
