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Citrulline is a non-essential amino acid, meaning that the body can manufacture it from other nutrients. Within the body, citrulline is converted to the amino acid L-arginine . Some of the proposed uses of citrulline supplements are based on raising levels of arginine. Citrulline also plays a role in a physiological process called “the urea cycle,” in which toxic ammonia is converted to urea.
Requirements/Sources
The body manufactures citrulline from the essential amino acid glutamine. Deficiency of citrulline is unlikely to occur.
Therapeutic Dosages
A typical dose of citrulline is 6–18 grams daily. It is commonly sold in the form of citrulline malate.